Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26133844 | 0.89 | GPR119 (0.48) | HDAC4KMT2AGPR119HDAC6NR3C1 | |
| SCHEMBL26498098 | 0.77 | TEAD1 (0.42) | — | |
| SCHEMBL20046185 | 0.77 | GPR119 (0.49) | KMT2AGPR119KDM4EPKM | |
| SCHEMBL29098488 | 0.77 | GPR119 (0.46) | GPR119 | |
| SCHEMBL2586290 | 0.75 | GPR119 (0.48) | KMT2AGPR119KDM4EPKM | |
| SCHEMBL26134135 | 0.75 | TEAD1 (0.49) | — | |
| SCHEMBL14637172 | 0.74 | STS (0.46) | HDAC4GPR119 | |
| SCHEMBL27459322 | 0.73 | GPR119 (0.47) | HDAC4KMT2AGPR119 | |
| SCHEMBL14635882 | 0.72 | GPR119 (0.48) | KMT2AGPR119KDM4EPKM | |
| SCHEMBL15950964 | 0.72 | GPR119 (0.50) | KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |