Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343056 | 0.85 | POLB (0.45) | POLBMAPTTP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL1343304 | 0.82 | POLB (0.46) | POLBMAPTTP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL2649813 | 0.82 | POLB (0.42) | POLBMAPTTP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL2661997 | 0.82 | ALDH1A1 (0.36) | POLBMAPTSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL1343909 | 0.81 | POLB (0.44) | POLBMAPTTP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL1343083 | 0.80 | POLB (0.44) | POLBMAPTTP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL1343200 | 0.80 | POLB (0.42) | POLBMAPTTP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL1343375 | 0.79 | SMN1; SMN2 (0.56) | POLBMAPTTP53SMN1; SMN2 | |
| SCHEMBL6692117 | 0.79 | POLB (0.42) | POLBMAPTTP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL1342210 | 0.79 | POLB (0.42) | POLBMAPTTP53SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |