Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343187 | 0.86 | LPAR1 (0.39) | ALDH1A1TSHRL3MBTL1LPAR1SMN1; SMN2 | |
| SCHEMBL1342497 | 0.83 | ITGB1 (0.42) | ALDH1A1TSHRCCNE1CDK2CDK5 | |
| SCHEMBL2661995 | 0.83 | ITGB1 (0.39) | ALDH1A1TSHRCCNE1CDK2CDK5 | |
| SCHEMBL1342668 | 0.82 | LPAR1 (0.39) | ALDH1A1TSHRL3MBTL1LPAR1SMN1; SMN2 | |
| SCHEMBL2649815 | 0.82 | POLB (0.40) | ALDH1A1TSHRL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL1343714 | 0.81 | LPAR1 (0.38) | L3MBTL1LPAR1SMN1; SMN2MAPK14MAPK13 | |
| SCHEMBL1340994 | 0.80 | LPAR1 (0.36) | ALDH1A1TSHRLPAR1SMN1; SMN2MYC | |
| SCHEMBL6695210 | 0.80 | CCNE1 (0.39) | ALDH1A1CCNE1CDK2CDK5LPAR1 | |
| SCHEMBL1343242 | 0.79 | LPAR1 (0.37) | L3MBTL1LPAR1SMN1; SMN2POLBMAPK14 | |
| SCHEMBL6695295 | 0.79 | AURKA (0.40) | CDK2LPAR1MAPK14AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |