Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648338 | 0.90 | GCGR (0.46) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2647426 | 0.90 | SLC10A2 (0.42) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2647427 | 0.90 | SLC10A2 (0.42) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2648215 | 0.88 | MAPT (0.48) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2648214 | 0.88 | MAPT (0.48) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2649051 | 0.88 | MAPT (0.45) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2647468 | 0.88 | SLC10A2 (0.44) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2647466 | 0.88 | SLC10A2 (0.44) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2647505 | 0.85 | SLC10A2 (0.45) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2647508 | 0.85 | SLC10A2 (0.45) | SLC10A2SMN1; SMN2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |