Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647505 | 1.00 | SLC10A2 (0.45) | SLC10A2GCGRHTTALDH1A1GAA | |
| SCHEMBL2649262 | 0.89 | GCGR (0.50) | SLC10A2GCGRALDH1A1MAPTNPSR1 | |
| SCHEMBL2649264 | 0.89 | GCGR (0.50) | SLC10A2GCGRALDH1A1MAPTNPSR1 | |
| SCHEMBL2648338 | 0.88 | GCGR (0.46) | SLC10A2GCGRHTTALDH1A1GAA | |
| SCHEMBL2648651 | 0.87 | SLC10A2 (0.43) | SLC10A2GCGRHTTALDH1A1GAA | |
| SCHEMBL2648656 | 0.87 | SLC10A2 (0.43) | SLC10A2GCGRHTTALDH1A1GAA | |
| SCHEMBL2647468 | 0.87 | SLC10A2 (0.44) | SLC10A2GCGRHTTALDH1A1GAA | |
| SCHEMBL2647466 | 0.87 | SLC10A2 (0.44) | SLC10A2GCGRHTTALDH1A1GAA | |
| SCHEMBL2649455 | 0.86 | SLC10A2 (0.43) | SLC10A2GCGRHTTALDH1A1GAA | |
| SCHEMBL2647327 | 0.86 | SLC10A2 (0.43) | SLC10A2GCGRHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |