Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26499316 | 0.94 | KMT2A (0.44) | ALDH1A1KMT2AMAPTSIGMAR1HTR1A | |
| SCHEMBL26499306 | 0.88 | DRD2 (0.51) | ALDH1A1SIGMAR1KCNH2CYP2C19MCHR1 | |
| SCHEMBL26499309 | 0.81 | KCNH2 (0.47) | KMT2AHTR1AKCNH2MCHR1KDM4E | |
| SCHEMBL26499319 | 0.77 | PPARD (0.46) | ALDH1A1MAPTPPARGPPARDPPARA | |
| SCHEMBL26499297 | 0.77 | MAPT (0.47) | ALDH1A1MAPTMCHR1TSHRPPARG | |
| SCHEMBL11973435 | 0.76 | CYP2D6 (0.45) | ALDH1A1HTR1ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL26499313 | 0.75 | PPARD (0.45) | MAPTMCHR1PPARGPPARDPPARA | |
| SCHEMBL22349797 | 0.74 | PPARD (0.48) | ALDH1A1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL31548631 | 0.72 | HTR1A (0.45) | ALDH1A1SIGMAR1HTR1AKCNH2MCHR1 | |
| SCHEMBL31548630 | 0.72 | HTR1A (0.45) | ALDH1A1SIGMAR1HTR1AKCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321082-A1 | USE OF TRIAZOLE ANALOGUES FOR INHIBITION OF A TRIPARTITE VOR PROTEIN COMPLEX IN MULTICELLULAR ORGANISMS | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20230321082-A1 | USE OF TRIAZOLE ANALOGUES FOR INHIBITION OF A TRIPARTITE VOR PROTEIN COMPLEX IN MULTICELLULAR ORGANISMS | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321082-A1 | USE OF TRIAZOLE ANALOGUES FOR INHIBITION OF A TRIPARTITE VOR PROTEIN COMPLEX IN MULTICELLULAR ORGANISMS | RABL3, VAPA, VAPB | ALDH1A1 4596/4885KMT2A 4618/4885MAPT 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.