Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | RORA | P35398 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343069 | 0.95 | RORC (0.39) | RORCKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1343137 | 0.94 | RORC (0.39) | RORCKDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL2648842 | 0.93 | RORC (0.33) | RORCKDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL2649974 | 0.90 | KDM4E (0.33) | RORCKDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL1343411 | 0.87 | ALDH1A1 (0.37) | RORCKDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL1340537 | 0.87 | RORC (0.36) | RORCKDM4ESMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL1343404 | 0.86 | ALDH1A1 (0.38) | RORCKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1342180 | 0.86 | RORC (0.36) | RORCKDM4ERAB9ASMN1; SMN2TP53 | |
| SCHEMBL1342536 | 0.85 | MAPT (0.37) | RORCRAB9AALDH1A1NPC1NPSR1 | |
| SCHEMBL1340655 | 0.85 | RORC (0.40) | RORCKDM4ERAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |