Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104845 | 0.80 | ADK (0.54) | ADKSMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL3354773 | 0.80 | ADK (0.51) | ADKSMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL783019 | 0.80 | ADK (0.51) | ADKSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL22744419 | 0.70 | MAP4K4 (0.48) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL436384 | 0.69 | GAA (0.57) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL14355880 | 0.68 | ADK (0.52) | ADKSMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL869242 | 0.67 | GAA (0.51) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL15716531 | 0.67 | IKBKB (0.56) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL18873093 | 0.67 | RARA (0.50) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL17087999 | 0.67 | ELANE (0.38) | RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076849-A1 | INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR | ORIC PHARMACEUTICALS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |