Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647043 | 0.78 | EPHX1 (0.55) | SMN1; SMN2MAPK1EPHX1ALDH1A1HPGD | |
| SCHEMBL2650064 | 0.75 | GCK (0.42) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL23582773 | 0.75 | LOXL2 (0.49) | SMN1; SMN2MAPK1ALDH1A1HDAC1HDAC6 | |
| SCHEMBL28393119 | 0.74 | LOXL2 (0.51) | SMN1; SMN2MAPK1EPHX1ALDH1A1HDAC1 | |
| SCHEMBL2654208 | 0.73 | GCK (0.47) | SMN1; SMN2MAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL2659503 | 0.73 | EPHX1 (0.55) | SMN1; SMN2EPHX1ALDH1A1LOXL2MEN1 | |
| SCHEMBL23792335 | 0.72 | LOXL2 (0.53) | SMN1; SMN2MAPK1ALDH1A1HDAC1HDAC6 | |
| SCHEMBL2252275 | 0.71 | CYP4A11 (0.51) | SMN1; SMN2MAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL2686297 | 0.71 | CTSS (0.51) | — | |
| SCHEMBL2250651 | 0.71 | LOXL2 (0.50) | SMN1; SMN2MAPK1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594867-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | Prosidion Limited (GB) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004072031-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | PROSIDION LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |