Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342099 | 0.88 | GHSR (0.39) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1340569 | 0.88 | ALDH1A1 (0.37) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1342140 | 0.84 | MAPT (0.38) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1342564 | 0.83 | ALDH1A1 (0.39) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1342746 | 0.80 | GHSR (0.40) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1342468 | 0.79 | GHSR (0.40) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1343043 | 0.79 | GHSR (0.43) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1341204 | 0.79 | GHSR (0.39) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1339126 | 0.78 | GCK (0.45) | GHSRCHRNA4SLC6A3ALDH1A1MAPT | |
| SCHEMBL1342690 | 0.78 | CASR (0.39) | GHSRCHRNA4SLC6A3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |