Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26501211 | 0.94 | PAOX (0.45) | PAOXHTR7HRH2HRH1ALDH1A1 | |
| SCHEMBL26501212 | 0.94 | PAOX (0.45) | PAOXHTR7HRH2HRH1ALDH1A1 | |
| SCHEMBL26501213 | 0.83 | HRH2 (0.42) | HTR7HRH2HRH1 | |
| SCHEMBL12247050 | 0.81 | HRH3 (0.39) | PAOXHRH2HRH1ALDH1A1MAPT | |
| SCHEMBL22560691 | 0.80 | HRH3 (0.41) | ALDH1A1HRH3 | |
| SCHEMBL13455664 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL22560529 | 0.78 | ALDH1A1 (0.38) | KCNH2CACNA1IALDH1A1HRH3 | |
| SCHEMBL26501209 | 0.77 | PAOX (0.43) | PAOXHTR7HRH2HRH1DRD2 | |
| SCHEMBL21497288 | 0.76 | PAOX (0.54) | PAOXHTR7ALDH1A1 | |
| SCHEMBL26382167 | 0.76 | PAOX (0.54) | PAOXHTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | KRAS, MDM2, NRAS | PAOX 1898/4885KCNH2 4868/4885CACNA1I 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.