Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 12/20 | 0.36 |
| ▸ | HRH1 | P35367 | 12/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26741730 | 0.80 | MEN1 (0.41) | ALDH1A1HRH3HRH2HRH1SMN1; SMN2 | |
| SCHEMBL26501254 | 0.78 | GAA (0.37) | ALDH1A1HRH3HRH2HRH1ALOX15 | |
| SCHEMBL26743000 | 0.78 | CHRM5 (0.53) | ALDH1A1HRH3HRH2HRH1SMN1; SMN2 | |
| SCHEMBL26501256 | 0.77 | HRH2 (0.39) | HRH3HRH2HRH1DRD2 | |
| SCHEMBL470994 | 0.77 | EPHX2 (0.44) | ALDH1A1HRH2HRH1SMN1; SMN2MAPT | |
| SCHEMBL29316649 | 0.76 | SIGMAR1 (0.40) | ALDH1A1CYP3A4CYP2D6ALOX15CYP2C19 | |
| SCHEMBL4086161 | 0.76 | ALDH1A1 (0.54) | ALDH1A1POLBCYP3A4CYP2D6PKM | |
| SCHEMBL24966180 | 0.76 | ALDH1A1 (0.43) | ALDH1A1POLBCYP3A4CYP2D6PKM | |
| SCHEMBL21421559 | 0.76 | HRH2 (0.35) | HRH3HRH2HRH1 | |
| SCHEMBL26743342 | 0.75 | HRH2 (0.40) | ALDH1A1HRH2HRH1PKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | KRAS, MDM2, NRAS | ALDH1A1 3243/4885POLB 2030/4885HRH3 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.