Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 14/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747663 | 0.85 | PANK3 (0.74) | PANK3TRPV1 | |
| SCHEMBL26501600 | 0.84 | PANK3 (0.79) | PANK3TRPV1ALDH1A1MAPT | |
| SCHEMBL26501285 | 0.78 | PANK3 (0.79) | PANK3KDM4EALDH1A1 | |
| SCHEMBL26501605 | 0.78 | PANK3 (0.63) | PANK3TRPV1MAPT | |
| SCHEMBL23657515 | 0.76 | PANK3 (0.51) | PANK3TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL21406450 | 0.73 | PANK3 (1.00) | PANK3TRPV1MAPT | |
| SCHEMBL26501631 | 0.73 | PANK3 (0.77) | PANK3TRPV1 | |
| SCHEMBL26501700 | 0.72 | PTPN1 (0.40) | TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL19748515 | 0.72 | PANK3 (1.00) | PANK3TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL27702496 | 0.71 | BPTF (0.48) | PANK3TRPV1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321092-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321092-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | HMGCR, GCDH, CYP11A1 | PANK3 1573/4885TRPV1 4795/4885KDM4E 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.