Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26501320 | 1.00 | GNAI3 (0.36) | GNAI3GNAI1GNAO1KCNQ3KCNQ2 | |
| SCHEMBL26505142 | 0.85 | GNAI3 (0.39) | GNAI3GNAI1GNAO1TPSAB1TPSD1 | |
| SCHEMBL26501276 | 0.81 | CHRM3 (0.35) | KCNQ3KCNQ2HTR1ACHRM2CHRM4 | |
| SCHEMBL26501275 | 0.78 | PAOX (0.35) | HTR7HTR1ACHRM2CHRM4CHRM5 | |
| SCHEMBL26501277 | 0.78 | PAOX (0.35) | HTR7HTR1ACHRM2CHRM4CHRM5 | |
| SCHEMBL26501314 | 0.77 | HRH2 (0.42) | HTR7HTR1ADRD2HRH2HRH1 | |
| SCHEMBL26742318 | 0.76 | NPC1 (0.51) | GNAI3GNAI1GNAO1CHRM2CHRM4 | |
| SCHEMBL26501345 | 0.72 | GBA1 (0.35) | GNAI3GNAI1GNAO1 | |
| SCHEMBL24942994 | 0.72 | ITGB3 (0.43) | GNAI3GNAI1GNAO1NPC1 | |
| SCHEMBL26302335 | 0.72 | GNAI3 (0.54) | GNAI3GNAI1GNAO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | KRAS, MDM2, NRAS | GNAI3 271/4885GNAI1 219/4885GNAO1 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.