Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GLS | O94925 | 4/20 | 0.49 |
| ▸ | CCNC | P24863 | 3/20 | 0.49 |
| ▸ | CDK8 | P49336 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 8/20 | 0.49 |
| ▸ | CA1 | P00915 | 8/20 | 0.49 |
| ▸ | CA2 | P00918 | 8/20 | 0.49 |
| ▸ | CA4 | P22748 | 8/20 | 0.49 |
| ▸ | CA7 | P43166 | 8/20 | 0.49 |
| ▸ | CA9 | Q16790 | 8/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748833 | 0.87 | PANK3 (0.64) | EPHX2TP53EPHX1NFKB1NFKB2 | |
| SCHEMBL19748831 | 0.87 | PANK3 (0.64) | EPHX2TP53EPHX1NFKB1NFKB2 | |
| SCHEMBL26501529 | 0.84 | PANK3 (0.48) | GLSPANK3 | |
| SCHEMBL26501525 | 0.84 | PANK3 (0.48) | GLSPANK3 | |
| SCHEMBL26502384 | 0.81 | GLS (0.45) | GLS | |
| SCHEMBL26501555 | 0.81 | KMT2A (0.59) | EPHX2TP53SMN1; SMN2PANK3 | |
| SCHEMBL18890179 | 0.80 | GLS (0.53) | SMN1; SMN2GLSCA12CA1CA2 | |
| SCHEMBL26502436 | 0.79 | PANK3 (0.44) | EPHX2GLSPANK3 | |
| SCHEMBL21424077 | 0.77 | PANK3 (0.66) | EPHX2TP53EPHX1NFKB1NFKB2 | |
| SCHEMBL26501600 | 0.77 | PANK3 (0.79) | TP53SMN1; SMN2PANK3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321092-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321092-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | HMGCR, GCDH, CYP11A1 | EPHX2 1708/4885TP53 3054/4885EPHX1 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.