SCHEMBL26501764

SCHEMBL26501764

Bc1c(B)c(-c2c3ccccc3c(-c3cccc4oc5c6ccccc6ccc5c34)c3ccccc23)c(O)c(B)c1-c1c(B)c(O)c(O)c(O)c1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.36
CYP2C19 P33261 2/20 0.36
TSHR P16473 1/20 0.36
ARSA P15289 1/20 0.36
CDC25A P30304 1/20 0.36
CDC25C P30307 1/20 0.36
ABCG2 Q9UNQ0 2/20 0.35
CYP1A1 P04798 5/20 0.33
CYP1A2 P05177 5/20 0.33
CYP1B1 Q16678 5/20 0.33
TDP1 Q9NUW8 2/20 0.32
PSMD14 O00487 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23943263 0.90 CYP3A4 (0.38) CYP3A4CYP2C19TSHRARSACDC25A
SCHEMBL24735267 0.89 ARSA (0.38) CYP3A4CYP2C19TSHRARSACDC25A
SCHEMBL26511888 0.87 CYP3A4 (0.34) CYP3A4CYP2C19TSHRARSACDC25A
SCHEMBL26520484 0.86 ALOX5 (0.35) CYP3A4CYP2C19TSHRABCG2CYP1A1
SCHEMBL26502545 0.85 CYP3A4 (0.33) CYP3A4CYP2C19TSHRARSACDC25A
SCHEMBL19774356 0.82 ALOX5 (0.39) CYP3A4CYP2C19MEN1TP53CYP2D6
SCHEMBL26502453 0.81 CYP3A4 (0.35) CYP3A4CYP2C19TSHRARSACDC25A
SCHEMBL26591498 0.81 ARSA (0.37) CYP3A4CYP2C19TSHRARSACDC25A
SCHEMBL26504907 0.80 MAOA (0.38) CYP3A4CYP2C19TSHRCYP1A2TDP1
SCHEMBL22541942 0.80 ARSA (0.42) CYP3A4CYP2C19TSHRARSACDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257657-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE Idemitsu Kosan Co.,Ltd. (JP) 2023-10-11 EP disclosed