Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341323 | 0.93 | KMT2A (0.37) | NTRK1MEN1KMT2AMAPTTP53 | |
| SCHEMBL1342597 | 0.92 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2NTRK1MEN1KMT2A | |
| SCHEMBL2649174 | 0.92 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NTRK1MEN1KMT2A | |
| SCHEMBL1343044 | 0.86 | MYC (0.37) | NTRK1MEN1KMT2AHSD17B10GCK | |
| SCHEMBL1342983 | 0.86 | LPAR1 (0.35) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL1342830 | 0.86 | TSHR (0.41) | ALDH1A1SMN1; SMN2NTRK1NPC1RAB9A | |
| SCHEMBL1340627 | 0.85 | NTRK1 (0.39) | ALDH1A1SMN1; SMN2NTRK1MAPTNPC1 | |
| SCHEMBL1341150 | 0.85 | PKM (0.41) | ALDH1A1SMN1; SMN2NTRK1KMT2AMAPT | |
| SCHEMBL1342373 | 0.84 | MKNK2 (0.34) | NTRK1MAPTTP53HSD17B10CCNE1 | |
| SCHEMBL1341387 | 0.84 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NTRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |