Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360913 | 1.00 | CA12 (0.48) | CA12CA9ARKMT2AMEN1 | |
| SCHEMBL30055555 | 0.90 | RAB9A (0.46) | CA12CA9ARKMT2AMEN1 | |
| SCHEMBL20839050 | 0.90 | RAB9A (0.46) | CA12CA9ARKMT2AMEN1 | |
| SCHEMBL30055832 | 0.88 | ALDH1A1 (0.51) | ARKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL20848101 | 0.88 | ALDH1A1 (0.51) | ARKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL20839063 | 0.88 | ALDH1A1 (0.56) | CA12CA9ARKMT2AMEN1 | |
| SCHEMBL20839060 | 0.88 | ALDH1A1 (0.56) | CA12CA9ARKMT2AMEN1 | |
| SCHEMBL30058125 | 0.87 | ALDH1A1 (0.57) | CA12CA9ARKMT2AMEN1 | |
| SCHEMBL20839376 | 0.87 | ALDH1A1 (0.57) | CA12CA9ARKMT2AMEN1 | |
| SCHEMBL30360854 | 0.86 | RAB9A (0.47) | CA12CA9ARKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684762-B1 | COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2023-05-03 | — | — | EP | disclosed |