Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436416 | 0.82 | LOX (0.57) | LOXL3MBTL1LOXL2LMNAPPARG | |
| SCHEMBL3149551 | 0.77 | PSIP1 (0.37) | LOXL3MBTL1LOXL2 | |
| SCHEMBL2997802 | 0.76 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL2606680 | 0.73 | KMT2A (0.52) | LOXL3MBTL1LOXL2LMNANPSR1 | |
| SCHEMBL15880558 | 0.71 | LOX (0.48) | LOXL3MBTL1LOXL2LMNAPPARG | |
| SCHEMBL1164361 | 0.71 | HTT (0.50) | LOXLMNANPSR1 | |
| SCHEMBL3464178 | 0.71 | LOX (0.44) | LOXL3MBTL1LOXL2LMNAPPARG | |
| SCHEMBL13874742 | 0.71 | LOX (0.48) | LOXL3MBTL1LOXL2NPSR1 | |
| SCHEMBL10050617 | 0.71 | L3MBTL1 (0.47) | LOXL3MBTL1 | |
| SCHEMBL3202558 | 0.70 | LOX (0.43) | LOXL3MBTL1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063194-A1 | HETEROARYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |
| EP-0759924-A1 | OLIGOTHIOPHENES | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995030679-A1 | OLIGOTHIOPHENES | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-16 | — | — | WO | disclosed |