Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652155 | 0.82 | FOLH1 (0.50) | ALDH1A1HIF1ATSHRMAPTALOX15 | |
| SCHEMBL8954678 | 0.77 | HIF1A (0.42) | ALDH1A1LMNAHIF1ATSHRHSD17B10 | |
| SCHEMBL8368182 | 0.77 | HIF1A (0.42) | ALDH1A1LMNAHIF1ATSHRHSD17B10 | |
| SCHEMBL8368183 | 0.77 | HIF1A (0.42) | ALDH1A1LMNAHIF1ATSHRHSD17B10 | |
| SCHEMBL2650417 | 0.77 | TSHR (0.53) | ALDH1A1TSHRMAPTKMT2ASLC6A3 | |
| SCHEMBL18801447 | 0.76 | NCEH1 (0.46) | ALDH1A1HIF1ATSHRMAPTKMT2A | |
| SCHEMBL10913663 | 0.76 | SLC6A3 (0.51) | ALDH1A1LMNATSHRMAPTKMT2A | |
| SCHEMBL10360804 | 0.76 | ALDH1A1 (0.77) | ALDH1A1LMNAHIF1ATSHRHSD17B10 | |
| SCHEMBL70322 | 0.76 | ALDH1A1 (0.66) | ALDH1A1LMNAHIF1ATSHRHSD17B10 | |
| SCHEMBL156281 | 0.76 | ALDH1A1 (0.66) | ALDH1A1LMNAHIF1ATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015757-A1 | Novel Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | US | disclosed |
| WO-2005058845-A2 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015757-A1 | Novel Glucagon Antagonists/Inverse Agonists | GLP1R, GCGR, GIPR | ALDH1A1 4836/4885LMNA 4123/4885HIF1A 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.