Coumarin

Coumarin

SCHEMBL265069

C=Cc1ccccc1.O=c1ccc2ccccc2o1

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.69
CA9 Q16790 7/20 0.69
CA1 P00915 6/20 0.69
CA2 P00918 3/20 0.69
CA3 P07451 3/20 0.69
CA4 P22748 3/20 0.69
CA7 P43166 3/20 0.69
CA14 Q9ULX7 3/20 0.69
CA5A P35218 2/20 0.69
CA5B Q9Y2D0 2/20 0.69
CA6 P23280 2/20 0.69
MCL1 Q07820 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
LMNA P02545 1/20 0.69
SOST Q9BQB4 1/20 0.69
MTNR1A P48039 2/20 0.50
ACHE P22303 1/20 0.50
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
PGR P06401 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin SCHEMBL28832503 0.91 CA12 (0.57) CA12CA9CA1CA2CA3
Coumarin SCHEMBL16736994 0.87 CA12 (0.61) CA12CA9CA1CA2CA3
SCHEMBL7358531 0.85 CA12 (0.95) CA12CA9CA1CA2CA3
Coumarin SCHEMBL19183240 0.85 CA12 (0.95) CA12CA9CA1CA2CA3
Coumarin SCHEMBL7526019 0.84 CA12 (0.49) CA12CA9CA1CA2CA3
Coumarin SCHEMBL29154495 0.83 CA12 (0.91) CA12CA9CA1CA2CA3
Coumarin SCHEMBL21933142 0.83 CA12 (0.91) CA12CA9CA1CA2CA3
Coumarin SCHEMBL18669429 0.83 CA12 (0.91) CA12CA9CA1CA2CA3
Coumarin SCHEMBL25431834 0.83 CA12 (0.91) CA12CA9CA1CA2CA3
Coumarin SCHEMBL621751 0.83 CA12 (1.00) CA12CA9CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112708010-B Polymer microsphere emulsion and preparation method and application thereof 中国石油化工股份有限公司 2023-03-28 CN claimed
CN-112708010-A Polymer microsphere emulsion and preparation method and application thereof 中国石油化工股份有限公司 2021-04-27 CN claimed
US-8133411-B2 Fluorescent polymers soluble in an aqueous solution and a method for the production thereof BIOMERIEUX S.A. (FR) 2012-03-13 US disclosed
US-20080290321-A1 Fluorescent Polymers Soluble in an Aqueous Solution and a Method for the Production Thereof BIOMERIEUX S.A. (FR) 2008-11-27 US disclosed
WO-2007003782-A2 NOVEL FUNCTIONALISED TRANSFER AGENTS FOR CONTROLLED RADICAL POLYMERISATION RAFT, RAFT METHODS USING SAID TRANSFER AGENTS AND POLYMERS OBTAINABLE THEREBY BIOMERIEUX S.A. (FR) 2007-01-11 WO disclosed