Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarin SCHEMBL7633181 | 0.88 | CA12 (0.62) | CA12CA9CA1CA2CA3 | |
| Coumarin SCHEMBL265069 | 0.84 | CA12 (0.69) | CA12CA9CA1CA2CA3 | |
| Naphthalene SCHEMBL10727204 | 0.83 | ALDH1A1 (0.47) | CA1CA2ALDH1A1TSHRCYP2D6 | |
| Indene SCHEMBL9444068 | 0.81 | ALDH1A1 (0.52) | CA1CA2TDP1ALDH1A1TSHR | |
| Indene SCHEMBL200671 | 0.81 | ALDH1A1 (0.52) | CA1CA2TDP1ALDH1A1TSHR | |
| Indene SCHEMBL27901419 | 0.81 | ALDH1A1 (0.37) | CA1CA2ALDH1A1TSHRCYP2D6 | |
| Indene SCHEMBL8625326 | 0.80 | ALDH1A1 (0.50) | CA1CA2ALDH1A1TSHRCYP2D6 | |
| Coumarin SCHEMBL28832503 | 0.77 | CA12 (0.57) | CA12CA9CA1CA2CA3 | |
| Indene SCHEMBL27535655 | 0.76 | ALDH1A1 (0.45) | CA1CA2ALDH1A1TSHRCYP2D6 | |
| Indene SCHEMBL3169287 | 0.74 | ALDH1A1 (0.44) | CA12CA9CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002155256-A | HOT MELT ADHESIVE | TOYO CHEM CO LTD | 2002-05-28 | — | — | JP | disclosed |
| EP-0140296-B1 | IMPROVED COATED POLYCARBONATE ARTICLES | GENERAL ELECTRIC COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |
| US-4550058-A | AUTOMOBILES, THERMOFORMABILITY, THERMOPLASTICITY, HEAT AND CHEMICAL RESISTANCE | GENERAL ELECTRIC COMPANY (US) | 1985-10-29 | — | — | US | disclosed |
| EP-0140296-A2 | Improved coated polycarbonate articles | GENERAL ELECTRIC COMPANY (US) | 1985-05-08 | — | — | EP | disclosed |