Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.30 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.30 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23605005 | 1.00 | L3MBTL1 (0.33) | L3MBTL1MAPTRENCCNT1CDK9 | |
| SCHEMBL23605199 | 0.94 | REN (0.32) | L3MBTL1MAPTRENCCNT1CDK9 | |
| SCHEMBL26508589 | 0.93 | REN (0.34) | L3MBTL1MAPTRENCYP3A4PDE4B | |
| SCHEMBL23605444 | 0.93 | REN (0.34) | L3MBTL1MAPTRENCYP3A4PDE4B | |
| SCHEMBL23605437 | 0.93 | REN (0.34) | L3MBTL1MAPTRENCCNT1CDK9 | |
| SCHEMBL23605197 | 0.91 | KLK7 (0.35) | L3MBTL1MAPTRENCCNT1CDK9 | |
| SCHEMBL26508219 | 0.90 | REN (0.34) | L3MBTL1MAPTRENCCNT1CDK9 | |
| SCHEMBL23605435 | 0.90 | REN (0.34) | L3MBTL1MAPTRENCCNT1CDK9 | |
| SCHEMBL23605198 | 0.87 | L3MBTL1 (0.36) | L3MBTL1MAPTRENCCNT1CDK9 | |
| SCHEMBL26508177 | 0.87 | L3MBTL1 (0.36) | L3MBTL1MAPTRENCCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133667-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133667-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | L3MBTL1 778/4885MAPT 4006/4885REN 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.