Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 7/20 | 0.52 |
| ▸ | MPO | P05164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26508275 | 0.87 | HTR1D (0.55) | HTR1DHTR2ACDK4CCND1HTR1B | |
| SCHEMBL26508293 | 0.83 | HTR2A (0.70) | HTR1DHTR2ACDK4CCND1HTR1B | |
| SCHEMBL8506914 | 0.83 | HTR1D (0.71) | HTR1DHTR2ACDK4CCND1HTR1B | |
| SCHEMBL26508875 | 0.83 | HTR2A (0.73) | HTR1DHTR2AHTR1BMAPTMTNR1A | |
| SCHEMBL26508256 | 0.82 | HTR2A (0.67) | HTR1DHTR2AHTR1BMPOMEN1 | |
| SCHEMBL26508279 | 0.82 | HTR1D (0.55) | HTR1DHTR2ACDK4CCND1HTR1B | |
| SCHEMBL26508280 | 0.81 | HTR1D (0.57) | HTR1DHTR2ACDK4CCND1HTR1B | |
| SCHEMBL26508281 | 0.79 | HTR1D (0.56) | HTR1DHTR2ACDK4CCND1HTR1B | |
| Hydrochloric Acid SCHEMBL10566310 | 0.78 | HTR1D (0.56) | HTR1DHTR2ACDK4CCND1HTR1B | |
| Hydrochloric Acid SCHEMBL10566305 | 0.78 | HTR1D (0.56) | HTR1DHTR2ACDK4CCND1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322735-A1 | AZETIDINYL TRYPTAMINES AND METHODS OF TREATING PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322735-A1 | AZETIDINYL TRYPTAMINES AND METHODS OF TREATING PSYCHIATRIC DISORDERS | TPH2, TPH1, HTR2A | HTR1D 15/4885HTR2A 3/4885CDK4 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.