Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25698087 | 1.00 | BLM (0.47) | BLMLMNAMAPTPTPN1SLC1A3 | |
| SCHEMBL25697194 | 0.83 | BLM (0.35) | BLMLMNAPTPN1 | |
| SCHEMBL30852968 | 0.79 | LAP3 (0.44) | LMNASLC1A3SLC1A2FOLH1LAP3 | |
| SCHEMBL10828911 | 0.76 | BLM (0.42) | BLMLMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15389954 | 0.74 | SMN1; SMN2 (0.39) | MAPTSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2550058 | 0.73 | BLM (0.44) | BLMLMNAMAPTSLC1A3SLC1A2 | |
| SCHEMBL8102360 | 0.73 | BLM (0.48) | BLMLMNAFOLH1RARBKDM4C | |
| SCHEMBL5915125 | 0.73 | BLM (0.44) | BLMLMNAMAPTSLC1A3SLC1A2 | |
| SCHEMBL26509987 | 0.73 | KDM4E (0.32) | FOLH1 | |
| SCHEMBL28023430 | 0.72 | BLM (0.42) | BLMLMNAMAPTPTPN1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076983-A1 | PYRIDIZIN-3(2H)-ONE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 2023-05-04 | — | — | WO | disclosed |