Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26510079 | 0.83 | BLM (0.47) | BLMLMNAPTPN1 | |
| SCHEMBL25698087 | 0.83 | BLM (0.47) | BLMLMNAPTPN1 | |
| SCHEMBL25697183 | 0.76 | — | — | |
| SCHEMBL25697196 | 0.69 | BLM (0.42) | BLMCA1LMNA | |
| SCHEMBL7282520 | 0.67 | BLM (0.41) | BLMCA1LMNAPTPN1 | |
| SCHEMBL18092724 | 0.65 | BLM (0.47) | BLMCA1LMNA | |
| SCHEMBL4255452 | 0.65 | BLM (0.47) | BLMCA1LMNA | |
| SCHEMBL30852968 | 0.63 | LAP3 (0.44) | LMNA | |
| SCHEMBL6695690 | 0.63 | CA2 (0.44) | CA1 | |
| SCHEMBL1783849 | 0.63 | BLM (0.41) | BLMCA1LMNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183216-A1 | PYRIDIZIN-3(2H)-ONE DERIVATIVES | GILEAD SCIENCES, INC. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183216-A1 | PYRIDIZIN-3(2H)-ONE DERIVATIVES | PIR, CYP3A43, CYP1A2 | BLM 693/4885CA1 4820/4885LMNA 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.