Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24616403 | 0.88 | AR (0.33) | AR | |
| SCHEMBL26115443 | 0.81 | — | — | |
| SCHEMBL24616248 | 0.81 | ENPP1 (0.35) | — | |
| SCHEMBL24616033 | 0.76 | ENPP3 (0.31) | — | |
| SCHEMBL23301032 | 0.73 | CACNA1H (0.39) | — | |
| SCHEMBL20660532 | 0.73 | APP (0.37) | — | |
| SCHEMBL29656421 | 0.73 | CACNA1H (0.39) | — | |
| SCHEMBL30876101 | 0.73 | APP (0.37) | — | |
| SCHEMBL27053774 | 0.72 | — | — | |
| SCHEMBL11654423 | 0.72 | GPR35 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212548-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023183755-A1 | TRICYCLIC PYRIMIDONES | ERASCA, INC. (US) | 2023-09-28 | — | — | WO | disclosed |