Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649853 | 0.88 | GCK (0.32) | CYP3A4PDK2 | |
| SCHEMBL2650318 | 0.85 | GCK (0.32) | — | |
| SCHEMBL2650469 | 0.85 | GCK (0.32) | — | |
| SCHEMBL2650025 | 0.84 | GCK (0.33) | — | |
| SCHEMBL2650108 | 0.83 | GCK (0.45) | — | |
| SCHEMBL2650706 | 0.76 | TAS1R3 (0.34) | CYP3A4 | |
| SCHEMBL2646441 | 0.75 | TSHR (0.47) | CYP3A4 | |
| SCHEMBL2646437 | 0.75 | TSHR (0.47) | CYP3A4 | |
| SCHEMBL2650716 | 0.74 | RARA (0.34) | — | |
| SCHEMBL2649681 | 0.74 | GCK (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311504-A1 | TETRAZOLYL-PHENYL ACETAMIDE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014312-A1 | TETRAZOLYL-PHENYL ACETAMIDE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |