Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26512683 | 0.94 | KDM4E (0.31) | SMN1; SMN2NPC1RAB9AABCG2 | |
| SCHEMBL26512625 | 0.93 | MAPT (0.34) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL26513020 | 0.92 | MAPT (0.34) | TP53MAPTSMN1; SMN2NPC1NFKB1 | |
| SCHEMBL26512649 | 0.91 | TP53 (0.32) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL26512685 | 0.91 | GPR84 (0.33) | TP53MAPTSMN1; SMN2ABCB1ABCC1 | |
| SCHEMBL26512653 | 0.91 | CES2 (0.30) | — | |
| SCHEMBL26514699 | 0.91 | ENPP1 (0.32) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL26512629 | 0.91 | BRD4 (0.39) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL26512634 | 0.91 | BRD4 (0.39) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL26512914 | 0.90 | TP53 (0.31) | TP53MAPTSMN1; SMN2NPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |