Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 8/20 | 0.52 |
| ▸ | GCK | P35557 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423148 | 0.84 | FFAR2 (0.62) | FFAR2GCKKCNH2LMNAMEN1 | |
| SCHEMBL2642305 | 0.84 | FFAR2 (0.62) | FFAR2GCKKCNH2LMNAMEN1 | |
| SCHEMBL2651982 | 0.82 | FFAR2 (0.54) | FFAR2GCKKCNH2LMNAMEN1 | |
| SCHEMBL2642385 | 0.71 | FFAR2 (0.56) | FFAR2GCKKCNH2CYP3A4 | |
| SCHEMBL2645076 | 0.69 | FFAR2 (0.72) | FFAR2GCKKCNH2 | |
| SCHEMBL2645075 | 0.69 | FFAR2 (0.72) | FFAR2GCKKCNH2 | |
| SCHEMBL2657079 | 0.69 | FFAR2 (0.72) | FFAR2GCKKCNH2 | |
| SCHEMBL14423133 | 0.69 | FFAR2 (0.56) | FFAR2GCKKCNH2LMNAMEN1 | |
| SCHEMBL2642146 | 0.69 | FFAR2 (0.56) | FFAR2GCKKCNH2LMNAMEN1 | |
| SCHEMBL2656985 | 0.69 | FFAR2 (0.70) | FFAR2GCKKCNH2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095438-A9 | SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2004-12-23 | — | — | WO | disclosed |