Sugi Predict

Sugi Predict / Compounds / SCHEMBL265127

SCHEMBL265127

SCHEMBL265127

CCOC(=O)C(C)CC(C)C

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.49
▸ CYP2C19 P33261 1/20 0.49
▸ GAA P10253 2/20 0.47
▸ ALDH1A1 P00352 4/20 0.43
▸ LMNA P02545 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ ALOX15 P16050 1/20 0.40
▸ MGAM O43451 1/20 0.40
▸ SI P14410 1/20 0.40
▸ MGAM2 Q2M2H8 1/20 0.40
▸ SOAT1 P35610 1/20 0.40
▸ MMP8 P22894 1/20 0.37
▸ TRPA1 O75762 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ PPID Q08752 1/20 0.36
▸ RNPEP Q9H4A4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9271930 1.00 CYP3A4 (0.49) CYP3A4CYP2C19GAAALDH1A1LMNA
Phosphine SCHEMBL27450508 0.98 CYP3A4 (0.47) CYP3A4CYP2C19GAAALDH1A1LMNA
SCHEMBL18410487 0.90 CYP3A4 (0.56) CYP3A4CYP2C19GAAALDH1A1LMNA
SCHEMBL18856253 0.85 CYP3A4 (0.42) CYP3A4CYP2C19GAAALDH1A1LMNA
SCHEMBL12907779 0.83 CYP3A4 (0.47) CYP3A4CYP2C19GAAALDH1A1LMNA
SCHEMBL31301073 0.83 CYP3A4 (0.47) CYP3A4CYP2C19GAAALDH1A1LMNA
SCHEMBL16573686 0.83 CYP3A4 (0.47) CYP3A4CYP2C19GAAALDH1A1LMNA
SCHEMBL7222777 0.81 HCAR2 (0.38) CYP3A4CYP2C19GAAALDH1A1LMNA
SCHEMBL10960648 0.81 CYP3A4 (0.46) CYP3A4CYP2C19GAAALDH1A1LMNA
SCHEMBL13424249 0.81 CYP3A4 (0.46) CYP3A4CYP2C19GAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446698-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2023-03-28 — — CN disclosed
US-11584740-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-02-21 — — US disclosed
CN-112770632-B Fungicidal compositions 先正达农作物保护股份公司 2022-12-27 — — CN disclosed
CN-111093372-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2022-05-27 — — CN disclosed
CN-111050558-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2022-05-27 — — CN disclosed
CN-109952360-B Quantum dot dispersion, self-luminous photosensitive resin composition, color filter manufactured using the same, and image display device 东友精细化工有限公司 2022-03-22 — — CN disclosed
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-08 — — US disclosed
US-20220030867-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-02-03 — — US disclosed
EP-3601228-B1 MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2022-01-19 — — EP disclosed
EP-3681286-B1 MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2021-12-15 — — EP disclosed
US-7678740-B2 Avermectin and avermectin monosaccharide derivatives substituted in the 4″-or 4′-position having pesticidal properties MERIAL LIMITED (US) 2010-03-16 — — US disclosed
US-20090197834-A1 QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF ASTELLAS PHARMA INC. (JP) 2009-08-06 — — US disclosed
US-7378399-B2 Avermectins substituted in the 4″ and 4′-positions having pesticidal properties MERIAL LIMITED (US) 2008-05-27 — — US disclosed
US-7378399-B2 Avermectins substituted in the 4″ and 4′-positions having pesticidal properties MERIAL LIMITED (US) 2008-05-27 — — US disclosed
CN-1066150-C Bridged indoles as matrix metalloprotease inhibitors SYNTEX INC (US) 2001-05-23 — — CN disclosed
CN-1044249-C Matrix metalloprotease inhibitors SYNTEX INC (US) 1999-07-21 — — CN disclosed
CN-1180358-A Bridged indoles as matrix metalloprotease inhibitors SYNTEX INC (US) 1998-04-29 — — CN disclosed
EP-0309766-B1 N-acylamino acid derivatives and their use BANYU PHARMA CO LTD (JP) 1998-04-15 — — EP disclosed
CN-1134153-A Matrix metalloprotease inhibitors SYNTEX INC (US) 1996-10-23 — — CN disclosed
CN-1032786-A N-acyl amino acid derivative and uses thereof BANYU PHARMA CO LTD (JP) 1989-05-10 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 CYP3A4 473/4885CYP2C19 981/4885GAA 449/4885
US-20090197834-A1 QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF P2RY12, P2RY11, P2RY10 CYP3A4 1005/4885CYP2C19 281/4885GAA 4528/4885
US-11584740-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 CYP3A4 473/4885CYP2C19 981/4885GAA 449/4885
US-20220030867-A1 FUNGICIDAL COMPOSITIONS CYP1B1, CYP4B1, CYP3A43 CYP3A4 23/4885CYP2C19 4/4885GAA 3864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.