Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.36 |
| ▸ | BRAF | P15056 | 8/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342398 | 0.97 | KDR (0.36) | KDRBRAFSCN8ASCN10AFFAR2 | |
| SCHEMBL1342018 | 0.94 | LMNA (0.34) | — | |
| SCHEMBL2651271 | 0.87 | SCN10A (0.33) | SCN8ASCN10AHCRTR1FFAR2 | |
| SCHEMBL1340577 | 0.85 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL1342141 | 0.85 | SIRT4 (0.35) | FFAR2 | |
| SCHEMBL1341268 | 0.84 | CCNE1 (0.38) | — | |
| SCHEMBL1341979 | 0.84 | RXFP1 (0.33) | KDRBRAFFFAR2 | |
| SCHEMBL1343229 | 0.84 | MAPT (0.40) | — | |
| SCHEMBL2650083 | 0.84 | HCRTR1 (0.35) | KDRBRAFHCRTR1FFAR2 | |
| SCHEMBL1340110 | 0.83 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |