Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26512894 | 0.94 | KDM4E (0.32) | ACACAKDM4EHPGDKMT2ATDP1 | |
| SCHEMBL26512774 | 0.93 | BRD4 (0.39) | ACACAKDM4EHPGDTDP1ACP1 | |
| SCHEMBL26512783 | 0.93 | BRD4 (0.39) | ACACAKDM4EHPGDTDP1ACP1 | |
| SCHEMBL26512791 | 0.91 | ACACA (0.38) | ACACAKDM4EHPGDKMT2ATDP1 | |
| SCHEMBL26512767 | 0.91 | LMNA (0.32) | KMT2AMAPTLMNAMEN1 | |
| SCHEMBL26512877 | 0.90 | — | — | |
| SCHEMBL26512796 | 0.90 | ACACA (0.35) | ACACAKDM4EHPGDKMT2ATDP1 | |
| SCHEMBL26512788 | 0.90 | ACACA (0.35) | ACACAKDM4EHPGDKMT2ATDP1 | |
| SCHEMBL26512802 | 0.89 | — | — | |
| SCHEMBL26513004 | 0.89 | ACACA (0.38) | ACACAKDM4EHPGDKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |