Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK10 | O94804 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26512907 | 0.93 | STK10 (0.33) | STK10SLKRAF1BRAFPIK3CA | |
| SCHEMBL26513017 | 0.90 | STK10 (0.33) | STK10SLKRAF1BRAFPIK3CA | |
| SCHEMBL26512805 | 0.89 | PIK3CA (0.32) | PIK3CAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL26627991 | 0.89 | PDK2 (0.33) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL26512764 | 0.89 | MAPT (0.34) | PIK3CAKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL26627990 | 0.88 | RAB9A (0.36) | STK10SLKPIK3CAKDM4EALDH1A1 | |
| SCHEMBL26512777 | 0.88 | MAPT (0.40) | PIK3CAKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL26512802 | 0.88 | — | — | |
| SCHEMBL26512868 | 0.87 | MAPT (0.35) | PIK3CAKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL25600645 | 0.85 | HTR7 (0.33) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |