Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803424 | 0.92 | KIF11 (0.46) | KDM4EHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL26513304 | 0.90 | S1PR1 (0.47) | BACE1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL20378505 | 0.88 | CA12 (0.46) | ALDH1A1SMN1; SMN2ESR2CYP3A4LMNA | |
| SCHEMBL28803531 | 0.84 | CYP2C9 (0.48) | RAB9ANPC1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL28803610 | 0.80 | NFE2L2 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL24605277 | 0.79 | CYP3A4 (0.50) | NPC1ALDH1A1SMN1; SMN2CYP3A4LMNA | |
| Methyl Alcohol SCHEMBL28369464 | 0.76 | ESR2 (0.62) | BACE1RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL291776 | 0.76 | CA4 (0.68) | BACE1RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL17283658 | 0.76 | CA4 (0.68) | BACE1RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL9152375 | 0.76 | CA4 (0.68) | BACE1RAB9ANPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |