Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702451 | 0.85 | TP53 (0.46) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL1342960 | 0.85 | TP53 (0.47) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL6697382 | 0.85 | TP53 (0.47) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL6700223 | 0.84 | TP53 (0.44) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL1343039 | 0.84 | TP53 (0.46) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL2651340 | 0.84 | TP53 (0.42) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL1343466 | 0.83 | TP53 (0.45) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL1343733 | 0.82 | TP53 (0.46) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL6697734 | 0.82 | TP53 (0.41) | ALDH1A1TP53GAAAURKALMNA | |
| SCHEMBL6696150 | 0.80 | TP53 (0.46) | TP53GAAAURKALMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |