SCHEMBL26514879

SCHEMBL26514879

CSN(C)c1cc(C(C)C)ccc1C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
PTGS1 P23219 2/20 0.47
TRPA1 O75762 1/20 0.47
CACNA1C Q13936 1/20 0.47
HTT P42858 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
ALOX12 P18054 1/20 0.37
HIF1A Q16665 1/20 0.37
ACHE P22303 4/20 0.36
BCHE P06276 3/20 0.36
CRHR1 P34998 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
S1PR1 P21453 1/20 0.33
PTGS2 P35354 1/20 0.33
RNASEH1 O60930 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14228579 0.82 LMNA (0.54) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL23520055 0.78 LMNA (0.50) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL26519517 0.77 CYP1A2 (0.36) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL27334427 0.74 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CACHE
SCHEMBL23914169 0.74 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL25900783 0.74 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL24497503 0.73 LMNA (0.44) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL22607366 0.73 LMNA (0.44) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL18930326 0.73 LMNA (0.44) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL18931447 0.72 PTGS1 (0.46) LMNAPTGS1TRPA1CACNA1CHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257587-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2023-10-11 EP disclosed