Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342678 | 0.96 | ALDH1A1 (0.43) | MAPK1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL1342848 | 0.93 | MAPK1 (0.45) | MAPK1ALDH1A1SMN1; SMN2TP53GAA | |
| SCHEMBL2651526 | 0.88 | ALDH1A1 (0.34) | MAPK1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL1344232 | 0.84 | ALDH1A1 (0.47) | MAPK1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL6696934 | 0.81 | OGA (0.46) | MAPK1ALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL1344133 | 0.80 | MAPK1 (0.48) | MAPK1ALDH1A1SMN1; SMN2TP53GAA | |
| SCHEMBL6695257 | 0.78 | OGA (0.47) | SMN1; SMN2TP53GAACHRM3POLB | |
| SCHEMBL1344223 | 0.78 | TSHR (0.40) | — | |
| SCHEMBL1341969 | 0.78 | L3MBTL1 (0.51) | MAPK1ALDH1A1SMN1; SMN2TP53GAA | |
| SCHEMBL1343238 | 0.77 | L3MBTL1 (0.51) | MAPK1ALDH1A1SMN1; SMN2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |