SCHEMBL26516

SCHEMBL26516

[c]1ccc2cccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 2/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
CYP2E1 P05181 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2B6 P20813 1/20 0.33
CYP1A2 P05177 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
CYP3A4 P08684 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NOTUM Q6P988 1/20 0.32
MMP3 P08254 1/20 0.32
BCL2L1 Q07817 1/20 0.32
BACE1 P56817 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27605794 0.97 ALDH1A1 (0.40) ALDH1A1MAPK1RAB9ANPC1CYP2E1
SCHEMBL38202 0.89 ALDH1A1 (0.42) ALDH1A1MAPK1RAB9ANPC1CYP2E1
SCHEMBL41140 0.89 ALDH1A1 (0.42) ALDH1A1MAPK1RAB9ANPC1CYP2E1
SCHEMBL28544762 0.86 ALDH1A1 (0.40) ALDH1A1MAPK1RAB9ANPC1CYP2E1
SCHEMBL1535844 0.84 ALDH1A1 (0.38) ALDH1A1MAPK1RAB9ANPC1CYP2E1
SCHEMBL769634 0.84 ALDH1A1 (0.45) ALDH1A1MAPK1CYP2E1CYP2A6CYP2B6
SCHEMBL769959 0.84 ALDH1A1 (0.45) ALDH1A1MAPK1CYP2E1CYP2A6CYP2B6
SCHEMBL25097 0.84 ALDH1A1 (0.45) ALDH1A1MAPK1CYP2E1CYP2A6CYP2B6
SCHEMBL183516 0.83 ALDH1A1 (0.35) ALDH1A1RAB9AMEN1KMT2A
SCHEMBL1451004 0.82 ALDH1A1 (0.43) ALDH1A1MAPK1CYP2E1CYP2A6CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 36165 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324771-A Organic light-emitting device, electronic device, and heterocyclic compound 三星显示有限公司 2024-07-12 CN claimed
EP-4398362-A1 POLYMER SOLID ELECTROLYTE AND APPLICATION Nanjing Bochi New Energy Co., Ltd. (CN) 2024-07-10 EP claimed
US-12035550-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-09 US claimed
CN-118271347-A Heterocyclic compound, organic light-emitting device including the same, and electronic device 三星显示有限公司 2024-07-02 CN claimed
WO-2024131776-A1 BUFALIN DERIVATIVE AND PREPARATION METHOD THEREFOR, COMPOSITION, PREPARATION, AND APPLICATION 上海邈基生物科技有限公司 2024-06-27 WO claimed
CN-110277500-B Organic light emitting device 三星显示有限公司 2024-06-21 CN claimed
CN-112054128-B Heterocyclic compound and organic light-emitting device comprising same 三星显示有限公司 2024-06-18 CN claimed
CN-118164979-A Azaindole PI3K delta inhibitor, preparation method and application thereof 浙江大学 2024-06-11 CN claimed
US-20240188315-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-06 US claimed
US-12004417-B2 Heterocyclic compound and light-emitting device including same SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-04 US claimed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US claimed
US-4175956-A Electrophotosensitive materials for migration imaging processes EASTMAN KODAK COMPANY (US) 1979-11-27 US claimed
US-4175195-A REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN UNSATURATED KETONE OR ALDEHYDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-11-20 US claimed
US-4140681-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1979-02-20 US claimed
US-4131673-A INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1978-12-26 US claimed
US-4125604-A PEPTIDES, ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-11-14 US claimed
US-4101653-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US claimed
US-4097472-A INHIBITION AND SUPRESSION OF THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-27 US claimed
US-4093712-A ANTITHROMBOGENIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-06 US claimed
US-4066773-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-03 US claimed