SCHEMBL183516

SCHEMBL183516

[c]1ccccc2cccc1-2

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41140 0.94 ALDH1A1 (0.42) ALDH1A1MEN1RAB9AKMT2A
SCHEMBL38202 0.94 ALDH1A1 (0.42) ALDH1A1MEN1RAB9AKMT2A
SCHEMBL28544762 0.92 ALDH1A1 (0.40) ALDH1A1RAB9AKMT2A
SCHEMBL769959 0.90 ALDH1A1 (0.45) ALDH1A1
SCHEMBL25097 0.90 ALDH1A1 (0.45) ALDH1A1
SCHEMBL769634 0.90 ALDH1A1 (0.45) ALDH1A1
SCHEMBL1615164 0.84
SCHEMBL589437 0.84 MAOA (0.41) ALDH1A1MEN1KMT2A
SCHEMBL7951300 0.84 ALDH1A1 (0.33) ALDH1A1MEN1RAB9AKMT2A
SCHEMBL26567 0.84 MAOA (0.41) ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294246-B2 Substituted boronic acids and boronate esters as immunoproteasome inhibitors MERCK PATENT GMBH (DE) 2019-05-21 US claimed
CN-103052642-A Crystal of tricyclic pyrazolopyrimidine derivative DAIICHI SANKYO CO LTD 2013-04-17 CN claimed
CN-102333781-A Tricyclic pyrazolopyrimidine derivatives DAIICHI SANKYO CO LTD 2012-01-25 CN claimed
WO-2009003952-A2 COLUMN AND METHOD FOR PREPARING A BIOLOGICAL SAMPLE FOR PROTEIN PROFILING PRONOTA N.V. (BE) 2009-01-08 WO claimed
US-20240238460-A1 IMPROVED PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETING RADIOPHARMACEUTICALS AND USES THEREOF TELIX PHARMACEUTICALS INNOVATIONS PTY LTD (AU) 2024-07-18 US disclosed
EP-4399178-A1 PROCESS FOR THE PRODUCTION OF HYDROGEN THROUGH ELECTRIFICATION OF WATER GAS SHIFT REACTION TotalEnergies OneTech (FR) 2024-07-17 EP disclosed
EP-4399236-A1 DEGRADABLE CURING AGENTS, COMPOSITIONS AND CURABLE COMPOSITIONS THEREOF Vito NV (BE) 2024-07-17 EP disclosed
CN-118355022-A Nucleoside analogues for the treatment of parasitic infections 安特卫普大学 2024-07-16 CN disclosed
CN-118339204-A Dual catalyst composition 道达尔能源一技术比利时公司 2024-07-12 CN disclosed
CN-118339205-A Polymerization process using dual catalyst composition 道达尔能源一技术比利时公司 2024-07-12 CN disclosed
US-20240216291-A1 Nucleic Acid Containing Nanoparticles BIO TRIP B V (NL) 2024-07-04 US disclosed
US-20240209127-A1 NEW METALLOCENE CATALYST AND USE THEREOF TOTALENERGIES ONETECH BELGIUM (BE) 2024-06-27 US disclosed
US-6297008-B1 SIMPLE, SENSITIVE AND ACCURATE PROCESS BY HYBRIDIZING PROBE TO TARGET NUCLEIC ACID, ASSOCIATING CHEMILUMINESCENT COMPOUND OF DEFINED STRUCTURE WITH FORMED DOUBLE-STRAND, EXPOSING COMPOUND TO ACTIVATING COMPOUNDS, THEN DETECTING LUMINESCENCE CANON KABUSHIKI KAISHA (JP) 2001-10-02 US disclosed
CN-1219165-A Tricyclic compounds having activity specific for integrins, in particular alpha v beta 3 integrins, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them HOECHST MARION ROUSSEL CO (FR) 1999-06-09 CN disclosed
US-5846991-A Pyrazole derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-08 US disclosed
US-5840909-A Pyrazole derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-11-24 US disclosed
US-5817828-A HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS; VISION DEFECTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-06 US disclosed
EP-0837141-A2 Process for detecting target nucleic acid, process for quantifying the same, and pyrylium compound for chemiluminescence analysis CANON KABUSHIKI KAISHA (JP) 1998-04-22 EP disclosed
US-5721264-A EXHIBIT ANTAGONISTIC EFFECT AGAINST ANGIOTENSIN II; USEFUL FOR PREVENTION AND REMEDY OF HYPERTENSION, CONGESTIVE HEARTFAILURE, CHRONIC RENAL INSUFFICIENCY, ALDOSTERONISM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-24 US disclosed
EP-0693480-A1 PYRAZOLE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238460-A1 IMPROVED PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETING RADIOPHARMACEUTICALS AND USES THEREOF KLK3, FOLH1, CA14 ALDH1A1 3095/4885MEN1 81/4885RAB9A 292/4885
US-20240216291-A1 Nucleic Acid Containing Nanoparticles APOB, APOL1, TLR3 ALDH1A1 4030/4885MEN1 3590/4885RAB9A 2996/4885
US-10294246-B2 Substituted boronic acids and boronate esters as immunoproteasome inhibitors PSMB7, PSMA7, PSMB11 ALDH1A1 2896/4885MEN1 785/4885RAB9A 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.