Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPM1 | P06748 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360601 | 0.87 | MAP4K1 (0.47) | FYNMAP4K1ACVR1HRH3SYK | |
| SCHEMBL26516557 | 0.87 | MAP4K1 (0.47) | FYNMAP4K1ACVR1HRH3SYK | |
| SCHEMBL26516537 | 0.85 | FYN (0.53) | FYNMAP4K1ACVR1TGFBR1KCNH2 | |
| SCHEMBL26516612 | 0.82 | MAP4K1 (0.49) | FYNMAP4K1ACVR1TGFBR1KCNH2 | |
| SCHEMBL26516639 | 0.81 | ACVR1 (0.50) | FYNMAP4K1ACVR1HRH3KCNH2 | |
| SCHEMBL30360624 | 0.81 | ACVR1 (0.50) | FYNMAP4K1ACVR1HRH3KCNH2 | |
| SCHEMBL30360599 | 0.80 | FYN (0.51) | FYNMAP4K1ACVR1TGFBR1KCNH2 | |
| SCHEMBL30360604 | 0.80 | FYN (0.49) | FYNMAP4K1ACVR1TGFBR1KCNH2 | |
| SCHEMBL26120751 | 0.80 | FYN (0.49) | FYNMAP4K1ACVR1TGFBR1KCNH2 | |
| SCHEMBL26516706 | 0.80 | FYN (0.51) | FYNMAP4K1ACVR1TGFBR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322770-A1 | SUBSTITUTED HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL MYERS SQUIBB CO (US) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322770-A1 | SUBSTITUTED HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | TLR9, TLR3, TLR1 | FYN 1248/4885MAP4K1 2619/4885ACVR1 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.