Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26485477 | 0.86 | CYP1A2 (0.47) | CYP2C9CYP2C19MEN1KMT2AF2 | |
| SCHEMBL26482610 | 0.86 | KMT2A (0.47) | CYP2C9CYP2C19MEN1KMT2ATSHR | |
| SCHEMBL26519908 | 0.84 | EPHX2 (0.47) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL26485572 | 0.82 | GAA (0.44) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL26482347 | 0.81 | CYP2C19 (0.50) | CYP2C9CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL26107518 | 0.78 | MEN1 (0.44) | MEN1KMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL26482559 | 0.77 | CYP2C19 (0.43) | CYP2C9CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL26482402 | 0.74 | CYP2C19 (0.43) | CYP2C9CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL26482286 | 0.73 | CYP2C19 (0.47) | CYP2C9CYP2C19MEN1KMT2ACA1 | |
| SCHEMBL7840700 | 0.72 | MEN1 (0.58) | CYP2C9CYP2C19MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183886-A2 | COMPOSITIONS FOR AND METHODS OF MODULATING RNA STABILITY | DUKE UNIVERSITY (US) | 2023-09-28 | — | — | WO | disclosed |