Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26485477 | 0.91 | CYP1A2 (0.47) | HDAC2HDAC8HDAC6ALDH1A1MAOA | |
| SCHEMBL26485497 | 0.86 | EPHX2 (0.45) | EPHX2NR1H4HDAC1HDAC3HDAC4 | |
| SCHEMBL26517166 | 0.84 | CYP2C9 (0.45) | ALDH1A1LMNAMAPTPRSS1PRSS2 | |
| SCHEMBL7606673 | 0.83 | EPHX2 (0.68) | EPHX2NR1H4HDAC1HDAC3HDAC4 | |
| SCHEMBL26485572 | 0.81 | GAA (0.44) | ALDH1A1LMNAMAPTPRSS1PRSS2 | |
| SCHEMBL26108034 | 0.81 | EPHX2 (0.48) | EPHX2NR1H4HDAC1HDAC3HDAC4 | |
| SCHEMBL26106061 | 0.74 | CFD (0.46) | EPHX2NR1H4HDAC2HDAC8HDAC6 | |
| SCHEMBL456940 | 0.74 | THRB (0.54) | HDAC1HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL26485506 | 0.74 | TERT (0.42) | EPHX2NR1H4HDAC1HDAC3HDAC4 | |
| SCHEMBL26482808 | 0.73 | CYP1A2 (0.47) | EPHX2HDAC2HDAC8HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183886-A2 | COMPOSITIONS FOR AND METHODS OF MODULATING RNA STABILITY | DUKE UNIVERSITY (US) | 2023-09-28 | — | — | WO | disclosed |