Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 8/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23377510 | 0.81 | RIPK1 (0.46) | PYCR1ALDH1A1TAAR1LMNAHRH3 | |
| SCHEMBL9804910 | 0.80 | TSHR (0.52) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL9804592 | 0.78 | TSHR (0.50) | PYCR1MAOBALDH1A1TAAR1TSHR | |
| Hydrochloric Acid SCHEMBL9804606 | 0.77 | PYCR1 (0.46) | PYCR1MAOBALDH1A1TAAR1TSHR | |
| SCHEMBL399795 | 0.72 | HRH3 (0.64) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL15128047 | 0.72 | PYCR1 (0.67) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL10138441 | 0.71 | PYCR1 (0.46) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL18598042 | 0.69 | AOC3 (0.60) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL1241075 | 0.67 | KDM4E (0.69) | PYCR1MAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL15975291 | 0.66 | PYCR1 (0.41) | PYCR1MAOBKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192506-A1 | MALT1 MODULATORS AND USES THEREOF | RARIFIED BIOSCIENCES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |