Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696343 | 0.88 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPC1LMNARAB9A | |
| SCHEMBL6697170 | 0.87 | TP53 (0.42) | ALDH1A1KDM4ENPC1LMNARAB9A | |
| SCHEMBL2662061 | 0.87 | TP53 (0.37) | ALDH1A1KDM4ENPC1LMNARAB9A | |
| SCHEMBL2656451 | 0.84 | TP53 (0.43) | KDM4ENPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6697168 | 0.79 | TP53 (0.42) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6696522 | 0.78 | TP53 (0.42) | NPC1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL2650922 | 0.78 | TP53 (0.43) | NPC1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL6696356 | 0.77 | TP53 (0.42) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL6696350 | 0.77 | LMNA (0.45) | ALDH1A1KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL6695518 | 0.76 | TP53 (0.45) | KDM4ENPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |