Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 7/20 | 0.58 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26121996 | 0.82 | SSTR4 (0.80) | SSTR4SSTR1 | |
| SCHEMBL26121994 | 0.82 | SSTR4 (0.80) | SSTR4SSTR1 | |
| SCHEMBL26125218 | 0.82 | SSTR4 (0.80) | SSTR4SSTR1 | |
| SCHEMBL26523105 | 0.82 | EPHX1 (0.48) | SSTR4SSTR1ALDH1A1 | |
| SCHEMBL26523084 | 0.82 | SSTR4 (0.49) | SSTR4SSTR1ACKR3SIGMAR1 | |
| SCHEMBL4982545 | 0.79 | MCHR1 (0.66) | SSTR4HTR2AACKR3MCHR1CCR3 | |
| SCHEMBL26523074 | 0.78 | SSTR4 (0.60) | SSTR4SSTR1 | |
| SCHEMBL21748572 | 0.76 | SSTR4 (0.53) | SSTR4SSTR1SIGMAR1ALDH1A1 | |
| SCHEMBL20720786 | 0.75 | SSTR4 (0.54) | SSTR4HTR2AACKR3SIGMAR1SLC6A5 | |
| SCHEMBL30601831 | 0.74 | SSTR4 (1.00) | SSTR4SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187677-A1 | N-(PYRROLIDIN-3-YL OR PIPERIDIN-4-YL)ACETAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-05 | — | — | WO | disclosed |