Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 5/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.49 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26523249 | 0.86 | SSTR4 (0.53) | SSTR4SSTR1FPR3FPR2EPHX1 | |
| SCHEMBL26523041 | 0.82 | SSTR4 (0.58) | SSTR4SSTR1ACKR3SIGMAR1 | |
| SCHEMBL26126614 | 0.81 | SSTR4 (0.73) | SSTR4SSTR1FPR2 | |
| SCHEMBL26122040 | 0.80 | SSTR4 (0.69) | SSTR4SSTR1LMNA | |
| SCHEMBL26523155 | 0.79 | SSTR4 (0.70) | SSTR4SSTR1EPHX2NPC1RAB9A | |
| SCHEMBL3638096 | 0.79 | SIGMAR1 (0.58) | LMNAEPHX2NPC1RAB9ASIGMAR1 | |
| SCHEMBL7919878 | 0.77 | EPHX1 (0.50) | SSTR4SSTR1EPHX1EPHX2NPC1 | |
| SCHEMBL31682182 | 0.76 | SSTR4 (0.39) | SSTR4SSTR1 | |
| Trifluoroacetic Acid SCHEMBL30601840 | 0.75 | SSTR4 (0.62) | SSTR4SSTR1LMNA | |
| SCHEMBL26523105 | 0.74 | EPHX1 (0.48) | SSTR4SSTR1FPR3FPR2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187677-A1 | N-(PYRROLIDIN-3-YL OR PIPERIDIN-4-YL)ACETAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-05 | — | — | WO | disclosed |