Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FPR3 | P25089 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601814 | 0.86 | SSTR1 (0.56) | DNMT3AMEN1KMT2AMMP13CNR1 | |
| SCHEMBL30601837 | 0.85 | SSTR4 (0.48) | DNMT3AMEN1KMT2AMMP13CNR1 | |
| SCHEMBL3642671 | 0.83 | MEN1 (0.57) | EPHX1DNMT3AALDH1A1MEN1KMT2A | |
| SCHEMBL12491538 | 0.82 | CNR1 (0.47) | MEN1KMT2AKDM1AMMP13CNR1 | |
| SCHEMBL26523041 | 0.82 | SSTR4 (0.58) | ALDH1A1SSTR4SSTR1 | |
| SCHEMBL26523199 | 0.81 | SSTR4 (0.48) | EPHX1ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL5674705 | 0.80 | PKM (0.53) | DNMT3AMEN1KMT2AKDM1AMMP13 | |
| SCHEMBL4139902 | 0.80 | DNMT3A (0.56) | EPHX1DNMT3AALDH1A1MEN1KMT2A | |
| SCHEMBL2185224 | 0.80 | KDM1A (0.46) | MEN1KMT2AKDM1AMMP13CNR1 | |
| SCHEMBL2375919 | 0.79 | PKM (0.51) | EPHX1ALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187677-A1 | N-(PYRROLIDIN-3-YL OR PIPERIDIN-4-YL)ACETAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-05 | — | — | WO | disclosed |