Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 5/20 | 0.70 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26523249 | 0.86 | SSTR4 (0.53) | SSTR4SSTR1CHRM1CHRM3HPGD | |
| SCHEMBL26127350 | 0.82 | SSTR4 (1.00) | SSTR4SSTR1CHRM1CHRM3EPHX2 | |
| SCHEMBL26123784 | 0.82 | SSTR4 (0.78) | SSTR4SSTR1CHRM1CHRM3EPHX2 | |
| SCHEMBL30601806 | 0.82 | SSTR4 (1.00) | SSTR4SSTR1CHRM1CHRM3EPHX2 | |
| SCHEMBL30601834 | 0.82 | SSTR4 (0.78) | SSTR4SSTR1CHRM1CHRM3EPHX2 | |
| SCHEMBL8033661 | 0.80 | EPHX2 (0.75) | CHRM1CHRM3EPHX2SIGMAR1THRB | |
| SCHEMBL26523084 | 0.79 | SSTR4 (0.49) | SSTR4SSTR1EPHX2SIGMAR1NPC1 | |
| Trifluoroacetic Acid SCHEMBL30601822 | 0.77 | SSTR4 (0.87) | SSTR4SSTR1CHRM1CHRM3 | |
| SCHEMBL7919878 | 0.75 | EPHX1 (0.50) | SSTR4SSTR1EPHX2HPGDL3MBTL1 | |
| SCHEMBL30601825 | 0.73 | HSD11B1 (0.51) | SSTR4SSTR1CHRM3EPHX2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187677-A1 | N-(PYRROLIDIN-3-YL OR PIPERIDIN-4-YL)ACETAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-05 | — | — | WO | disclosed |