Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038190 | 0.95 | L3MBTL1 (0.53) | L3MBTL1MAPTNPSR1TAAR1ALDH1A1 | |
| SCHEMBL147184 | 0.87 | TAAR1 (0.66) | L3MBTL1MAPTNPSR1TAAR1ALDH1A1 | |
| SCHEMBL4059772 | 0.85 | L3MBTL1 (0.55) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL6681345 | 0.84 | THRB (0.55) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL6686357 | 0.84 | THRB (0.55) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL6682611 | 0.84 | THRB (0.55) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL6441843 | 0.84 | THRB (0.55) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL11332609 | 0.84 | THRB (0.55) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL28214185 | 0.84 | THRB (0.55) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL5247549 | 0.84 | L3MBTL1 (0.53) | L3MBTL1MAPTNPSR1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458382-A1 | AMIDE DERIVATIVES AS GK ACTIVATORS | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003055482-A1 | AMIDE DERIVATIVES AS GK ACTIVATORS | NOVO NORDISK A/S (DK) | 2003-07-10 | — | — | WO | disclosed |
| EP-0318233-A2 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |